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A versatile computational method for the determination of areas under the curve and moment curve following multidose drug administration

✍ Scribed by Toyoko S Yamashita; Hwei-Ling Lee; Michael D. Reed


Book ID
107769661
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
745 KB
Volume
23
Category
Article
ISSN
0020-7101

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A limited sampling model has been developed for Β―unarizine following a 30 mg oral dose in epileptic patients who were receiving phenytoin or carbamazepine or both, to estimate the area under the curve (AUC) and maximum plasma concentration (C max ). The model was developed using training data sets f