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Bi-allelic inactivation of the MEN1 tumor suppressor gene in human grade II astrocytoma☆

✍ Scribed by Wolfram Karges; Beate Karges; Leopold Ludwig; Peter H Heidemann


Book ID
117467793
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
99 KB
Volume
196
Category
Article
ISSN
0304-3835

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✍ Shuji Nomoto; Nobuhiro Haruki; Yoshio Tatematsu; Hiroyuki Konishi; Tetsuya Mitsu 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 109 KB 👁 2 views

The short arm of chromosome 1 is among the most frequently affected regions in various types of common adult cancers as well as in neuroblastoma. In a previous study of ours, frequent allelic imbalance at the TP73 locus at 1p36 was noted in lung cancer despite the absence of TP73 mutations. This sug