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BI-1 Regulates an Apoptosis Pathway Linked to Endoplasmic Reticulum Stress

✍ Scribed by Han-Jung Chae; Hyung-Ryong Kim; Chunyan Xu; Beatrice Bailly-Maitre; Maryla Krajewska; Stan Krajewski; Steven Banares; Janice Cui; Murat Digicaylioglu; Ning Ke; Shinichi Kitada; Edward Monosov; Michael Thomas; Christina L Kress; Jeremy R Babendure; Roger Y Tsien; Stuart A Lipton; John C Reed


Book ID
116753580
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
673 KB
Volume
15
Category
Article
ISSN
1097-2765

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## Abstract The chaperone glucose‐regulated protein, 78/immunoglobulin binding protein (GRP78/Bip), protects cells from cytotoxicity induced by DNA damage or endoplasmic reticulum (ER) stress. In this study, we showed that GRP78 is a major inducible protein in human non‐small cell lung cancer H460