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BFPP, a phloroglucinol derivative, induces cell apoptosis in human chondrosarcoma cells through endoplasmic reticulum stress

✍ Scribed by Ju-Fang Liu; Wei-Hung Yang; Yi-Chin Fong; Sheng-Chu Kuo; Chih-Shiang Chang; Chih-Hsin Tang

Book ID
113489109
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
545 KB
Volume
79
Category
Article
ISSN
0006-2952

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## Abstract Chondrosarcoma is a malignant primary bone tumor that responds poorly to both chemotherapy and radiation therapy. The aim of this study was to elucidate the mechanism of the novel Combretastatin A‐4 derivative, 2‐(furanyl)‐5‐(pyrrolidinyl)‐1‐(3,4,5‐trimethoxybenzyl)benzoimidazole (FPTB)