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Beyond ATM: The protein kinase landscape of the DNA damage response

✍ Scribed by Ariel Bensimon; Ruedi Aebersold; Yosef Shiloh


Book ID
113622581
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
999 KB
Volume
585
Category
Article
ISSN
0014-5793

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πŸ“œ SIMILAR VOLUMES


ATM and the DNA damage response
✍ Lavin, Martin F; Delia, Domenico; Chessa, Luciana πŸ“‚ Article πŸ“… 2006 πŸ› Nature Publishing Group 🌐 English βš– 188 KB
SQ/TQ cluster domains: concentrated ATM/
✍ Ana Traven; JΓΆrg Heierhorst πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 205 KB

ATM/ATR-like protein kinases play central roles in the maintenance of genome stability and phosphorylate numerous substrates in response to DNA damage, preferentially on SQ or TQ motifs. ATM/ATR substrates often contain several closely spaced SQ/TQ motifs in regions that have been termed SQ/TQ clust