High free beta human chorionic gonadotropin ( -hCG) and low alpha-fetoprotein (AFP) levels were found in 47 Asian Down's syndrome pregnancies (median values 2โข79 and 0โข77 MOM, respectively). At a 5 per cent false-positive rate, free -hCG alone would identify 46โข8 per cent of Down's syndrome pregnanc
โฆ LIBER โฆ
BETWEEN-PREGNANCY BIOLOGICAL VARIABILITY OF MATERNAL SERUM ALPHA- FETOPROTEIN AND FREE BETA hCG: IMPLICATIONS FOR DOWN SYNDROME SCREENING IN SUBSEQUENT PREGNANCIES
โ Scribed by KEVIN SPENCER
- Book ID
- 111697424
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 82 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0197-3851
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We have examined maternal urine concentrations of beta core, free beta human chorionic gonadotrophin (hCG), and total oestriol in 373 control pregnancies and 43 pregnancies affected by aneuploidy (including 22 cases of Down's syndrome) in an attempt to see if any of the analytes have a value in Down