Betaine can eliminate the base pair composition dependence of DNA melting
β Scribed by Rees, William A.; Yager, Thomas D.; Korte, John; Von Hippel, Peter H.
- Book ID
- 118262931
- Publisher
- American Chemical Society
- Year
- 1993
- Tongue
- English
- Weight
- 961 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0006-2960
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
We utilize the dynamic quenching of the triplet state of methylene blue by molecular oxygen to observe changes in the rate at which oxygen can penetrate the helix as a function of base-pair composition. The results indicate that the interior of the oligonucleotide dAdT is more accessible than dGdC t
The dependence of the net hydration of DNA on it,s base composition has been measured by density gradient ultrncentrifugation of three 1)l"u'A's in a series of cesium and lithium salt solutions of different water aativiticxs. 1t;strapolation to zero water activity showed the tkyeridcucc of thc parti