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.beta.-Carbolines as benzodiazepine receptor ligands. 1. Synthesis and benzodiazepine receptor interaction of esters of .beta.-carboline-3-carboxylic acid

✍ Scribed by Lippke, Klaus P.; Schunack, Walter G.; Wenning, Wolfgang; Mueller, Walter E.


Book ID
115502699
Publisher
American Chemical Society
Year
1983
Tongue
English
Weight
720 KB
Volume
26
Category
Article
ISSN
0022-2623

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Ξ²-carbolines as benzodiazepine receptor
✍ Klaus P. Lippke; Walter E. MΓΌller; Walter G. Schunack πŸ“‚ Article πŸ“… 1985 πŸ› John Wiley and Sons 🌐 English βš– 564 KB

Numerous 0-carboline-3-carboxamides were synthesized by amidation of p-carboline-3-carboxylic acid, with various amino acids and amino acid esters serving as arnine components, and tested in respect to their affinity for the benzodiazepine receptor in mouse brain membranes. The title compounds have