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Benzotriazole Reagents for the Syntheses of Fmoc-, Boc-, and Alloc-Protected Amino Acids

✍ Scribed by Ibrahim, Tarek; Tala, Srinivasa; El-Feky, Said; Abdel-Samii, Zakaria; Katritzky, Alan

Book ID
121707387
Publisher
Thieme Medical Publishers
Year
2011
Tongue
English
Weight
86 KB
Volume
2011
Category
Article
ISSN
0936-5214

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A new polymer-supported reagent for the
A new polymer-supported reagent for the Fmoc-protection of amino acids
✍ Rafael Chinchilla; David J Dodsworth; Carmen NΓ‘jera; JosΓ© M Soriano πŸ“‚ Article πŸ“… 2001 πŸ› Elsevier Science 🌐 French βš– 58 KB

A new polymer-supported Fmoc-OSu (Fmoc-P-OSu) has been prepared from polymer-bound N-hydroxysuccinimide (P-HOSu), and used as a solid-supported reagent for the Fmoc-protection of amino groups. The residual P-HOSu generated after the protection reaction can be separated by simple filtration and reuse