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Benzotriazole-assisted synthesis of ?-acylaminonitriles and a conceptually novel method for peptide elongation

✍ Scribed by Katritzky, Alan R.; Urogdi, Laszlo


Book ID
121328292
Publisher
Royal Society of Chemistry
Year
1990
Weight
658 KB
Volume
7
Category
Article
ISSN
1472-7781

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## Abstract After over a decade of studies on aspartic protease inhibitors and water‐soluble prodrugs, we have been developing a novel method, since 2003, called ‘__O__‐acyl isopeptide method’, for the synthesis of peptides containing difficult sequences. With our recent discoveries of ‘__O__‐acyl