ChemInform Abstract: 2-Substituted-4-met
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J. REGAN; ET AL. ET AL.
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Article
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2010
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John Wiley and Sons
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2-Substituted-4-methoxybenzimidazole-Based PDE4 Inhibitors. -The synthesis of a new family of phosphodiesterase PDE4 inhibitors based on a benzimidazole framework [cf. (VI), (X)] is described. Several of these compounds are orally bioavailable and show efficacy in in vivo models of inflammatory dis