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Benzo(A)pyrene metabolism and blast transformation in peripheral blood mononuclear cells from smoking and nonsmoking populations and lung cancer patients

✍ Scribed by James R. Jett; Harold L. Moses; Earl L. Branum; William F. Taylor; Robert S. Fontana


Publisher
John Wiley and Sons
Year
1978
Tongue
English
Weight
716 KB
Volume
41
Category
Article
ISSN
0008-543X

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Large interindividual variations in meta
✍ Gerald M. Cohen; Rekha Mehta; M. Meredith-Brown 📂 Article 📅 1979 🏛 John Wiley and Sons 🌐 French ⚖ 462 KB

## Abstract A very large variation (44‐fold) was observed in the ability of short‐term organ cultures of peripheral lung tissue from lung‐cancer patients to metabolize the environmental carcinogen benzo(a)pyrene to organic solvent‐soluble metabolites. The amounts of benzo(a)pyrene (2 μM) metabolize