Remote substituent effects on sterically hindered conformational changes have been reported for two classes of compounds. In one class, 4-substituted aniline derivatives(2) and 4-substituted 1-naphthylamine derivatives, (3) the
Benzene ring flipping in syn[2.2]metacyclophanes: effect of substituents
✍ Scribed by Shô Itô; Yoshisuke Nakasato; Hideaki Hioki; Miwa Nagaku; Yukiko Kan; Yoshimasa Fukazawa
- Book ID
- 108380416
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- French
- Weight
- 254 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0040-4039
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Dimethoxy[2.2]metacyclophane mainly gave a tetrahydropyrene structure and the other [2.n]metacyclophane derivatives (n=3-5) gave aromatic bromides like pseudo-ipso and/or pseudo-ortho dibromides in the reaction with bromine. They also gave benzyl bromides by cyclobutane ring-opening.
## Abstract For Abstract see ChemInform Abstract in Full Text.