Salvage treatment in patients with recurrent larged pelvic lymph nodes were identified in Hodgkin's disease is more effective when tumor another case, after a diagnosis of recurrent disburden is minimal. That is why more intensive ease in axilla. Those findings were interpreted follow-up strategies, including frequent imaging as relapse, and the patients underwent thoracottests, have been recently developed for the de-omy and laparotomy, respectively, for histologic tection of early relapse. However, as screening confirmation. The results showed progressively procedures become more sensitive, there is an transformed germinal centers and sarcoid-like increasing risk of false-positive results, demon-lesions, two benign proliferative disorders. strating nonmalignant proliferative disorders. When patients with Hodgkin's disease in remis-We describe three young patients who had lym-sion show new lymphadenopathy, even with phocyte-predominant or mixed-cellularity Hod-positive gallium scan, it seems mandatory to gkin's disease and were in clinical complete obtain tissue for histologic examination, even remission for 2.5-3 years after a combined treat-through invasive procedures such as laparotomy ment with chemotherapy and radiation. Imaging and thoracotomy, to avoid wrong diagnosis and tests revealed new gallium-avid lymphadenopa-unnecessary treatment. Med. Pediatr. Oncol. thy in the chest in two cases.