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Benextramine, a putative neuropeptide Y receptor antagonist, attenuates the termination of receptivity

✍ Scribed by John T. Clark

Book ID
116045752
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
500 KB
Volume
52
Category
Article
ISSN
0031-9384

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The identification and subsequent optimisation of a selective non-peptidic NPY Y2 antagonist series is described. This led to the development of amine 2, a selective, soluble NPY Y2 receptor antagonist with enhanced CNS exposure.