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Beneficial effects of inhibitors of prolyl 4-hydroxylase in CCl4-induced fibrosis of the liver in rats

✍ Scribed by Bickel, M.; Baader, E.; Brocks, D.G.; Engelbart, K.; Günzler, V.; Schmidts, H.L.; Vogel, G.H.

Book ID
122048327
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
528 KB
Volume
13
Category
Article
ISSN
0168-8278

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Selective inhibition of hepatic collagen
Selective inhibition of hepatic collagen accumulation in experimental liver fibrosis in rats by a new prolyl 4-hydroxylase inhibitor
✍ Martin Bickel; Karl-Heinz Baringhaus; Martin Gerl; Volkmar Günzler; Jiri Kanta; 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 273 KB 👁 1 views

Fibrosis and cirrhosis of the liver are often the result of chronic liver damage by a variety of different agents. Pathological accumulation of collagen, disruption of the lobular structure, and impaired hepatocellular function frequently lead to systemic involvement and fatal complications. Drugs i