✦ LIBER ✦

Bendamustine induces G2 cell cycle arrest and apoptosis in myeloma cells: the role of ATM-Chk2-Cdc25A and ATM-p53-p21-pathways

✍ Scribed by Leander Gaul; Sonja Mandl-Weber; Philipp Baumann; Bertold Emmerich; Ralf Schmidmaier

Publisher: Springer-Verlag
Year: 2007
Tongue: English
Weight: 513 KB
Volume: 134
Category: Article
ISSN: 1432-1335
DOI: 10.1007/s00432-007-0278-x

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Caffeine induces G2/M arrest and apoptos

Caffeine induces G2/M arrest and apoptosis via a novel p53-dependent pathway in NB4 promyelocytic leukemia cells

✍ Keisuke Ito; Tomonori Nakazato; Yoshitaka Miyakawa; Kenji Yamato; Yasuo Ikeda; M 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 342 KB 👁 1 views

## Abstract Methylxantine derivative, caffeine, is known to prevent the p53‐dependent apoptosis pathway via inhibition of ATM (ataxia telangiectasia mutated) kinase, which activates p53 by phosphorylation of the Ser‐15 residue. In contrast, it has been reported that caffeine induces p53‐mediated ap

P53 and p38 MAPK pathways are involved i

P53 and p38 MAPK pathways are involved in MONCPT-induced cell cycle G2/M arrest in human non-small cell lung cancer A549

✍ Chong Zhang; Hong Zhu; Xiaochun Yang; Jianshu Lou; Difeng Zhu; Wei lu; Qiaojun H 📂 Article 📅 2009 🏛 Springer-Verlag 🌐 English ⚖ 507 KB