Belimumab reduces autoantibodies, normalizes low complement levels, and reduces select B cell populations in patients with systemic lupus erythematosus
β Scribed by William Stohl; Falk Hiepe; Kevin M. Latinis; Mathew Thomas; Morton A. Scheinberg; Ann Clarke; Cynthia Aranow; Frank R. Wellborne; Carlos Abud-Mendoza; Douglas R. Hough; Lilia Pineda; Thi-Sau Migone; Z. John Zhong; William W. Freimuth; W. Winn Chatham; on behalf of the BLISS-52; BLISS-76 Study Groups
- Book ID
- 112002697
- Publisher
- John Wiley and Sons
- Year
- 2012
- Tongue
- English
- Weight
- 460 KB
- Volume
- 64
- Category
- Article
- ISSN
- 0004-3591
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## Abstract Peripheral blood lymphocytes from 14 patients with systemic lupus erythematosus, 5 patients with rheumatoid arthritis, and 10 normal subjects were cultured for 7 days with or without antiβIgM or antiβIgD antibodies, and IgGβ and IgMβsecreting cells were assayed by reverse hemolytic plaq