Behavioural effects of selective dopamine D-1 and D-2 agonists and antagonists in guinea-pigs
โ Scribed by Paul J. Brent
- Publisher
- Springer
- Year
- 1991
- Tongue
- English
- Weight
- 1001 KB
- Volume
- 104
- Category
- Article
- ISSN
- 0033-3158
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In hippocampal pyramidal cells (HPCs), Dopamine (DA) application (1 microM) produced, in 50% of recorded cells, an hyperpolarization of the resting membrane potential (r.m.p.) and an increase of the afterhyperpolarization (AHP) amplitude and duration in 79% of recorded cells. DA-induced effects on b
Seeman, P., D.E. Grigoriadis, and H.B. Niznik: Selectivity of agonists and antagonists at D2 dopamine receptors compared to D, and S2 receptors. Drug Dev. Res. 9:63-69, ## 1986. The common dopamine agonists (dopamine, apomorphine, ADTN, and N-propylnorapomorphine) are not selective for either D,