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Behavioral evidence implicating dopamine in sensorimotor arousal and norepinephrine in the sedative effects of antidepressant drugs

✍ Scribed by Larry Kokkinidis; Bryon D. McCarter


Publisher
Springer
Year
1990
Tongue
English
Weight
951 KB
Volume
100
Category
Article
ISSN
0033-3158

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The effects of clonidine on the antianxiety and sedation of benzodiazepines (BZD) were assessed respectively in rats trained in a two-lever diazepam cue discrimination procedure and in single-lever fixed-ratio (FR) waterreinforced performance. Clonidme (10-60 gg/kg) simnificanfly shifted to the left