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Distinct temporal phases in the behavioral pharmacology of LSD: dopamine D2receptor-mediated effects in the rat and implications for psychosis

โœ Scribed by Danuta Marona-Lewicka; Ronald A. Thisted; David E. Nichols


Publisher
Springer
Year
2005
Tongue
English
Weight
172 KB
Volume
180
Category
Article
ISSN
0033-3158

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## Abstract In this study we examined the selectivity of dopamine (DA) for rat striatal DA D~1~ and D~2~ receptors. In a Krebsโ€HEPES buffer, the K~i~ values of DA for D~1~ binding sites (labelled with [^3^H]SCH23390) and D~2~ binding sites (labelled with [^3^H]spiroperidol) in striatal membranes am