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Behavioral assessment of the Ts65Dn mouse, a model for down syndrome: Altered behavior in the elevated plus maze and open field

✍ Scribed by Mary E. Coussons-Read; Linda S. Crnic

Publisher: Springer US
Year: 1996
Tongue: English
Weight: 678 KB
Volume: 26
Category: Article
ISSN: 0001-8244
DOI: 10.1007/bf02361154

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## Abstract Agonist‐ and guanine‐nucleotide‐stimulated phospholipase C‐β (PLC) activity was characterized in crude plasma membrane preparations from cerebral cortex, hippocampus and cerebellum of Ts65Dn mice, a model for Down syndrome, and their control littermates. The levels of expression of PLC‐