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Behavioral and serotonergic response changes in the Dhcr7-HET mouse model of Smith–Lemli–Opitz syndrome

✍ Scribed by Korade, Z.; Folkes, O.M.; Harrison, F.E.


Book ID
125429929
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
342 KB
Volume
106
Category
Article
ISSN
0091-3057

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The Smith-Lemli-Opitz syndrome (SLOS) is a phenotypically variable metabolic malformation and mental retardation syndrome for which more than 80 mutations in the DHCR7 disease-causing gene have been described. The DHCR7 mutational spectra differ significantly in different areas of Europe, and severa