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Beeinflussung des Leber-Fettstoffwechsels durch Phytol

✍ Scribed by Karl Bernhard; Heribert Wagner

Publisher
John Wiley and Sons
Year
1954
Tongue
German
Weight
301 KB
Volume
37
Category
Article
ISSN
0018-019X

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✦ Synopsis

Abstract

After feeding rats with small quantities of phytol for 4 days the synthesis of fatty acids and the oxidation of acetate in liver slices have been studied with the aid of 1 ‐^14^C labelled acetate. Phytol caused a marked increase in the oxidation of acetate and a reduced synthesis of fatty acids. A “fasting effect” was excluded by estimations of glycogen in the livers, the control of food‐consumption and body weight. Tocopherol given in the place of phytol did not show the same effect. Evidently there is no splitting of the C‐bound side chain. Thus our former observations of a lipotropic effect of the phytol have been confirmed and extended.

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