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BCR/ABL: from molecular mechanisms of leukemia induction to treatment of chronic myelogenous leukemia

✍ Scribed by Salesse, Stephanie; Verfaillie, Catherine M

Book ID: 110067210
Publisher: Nature Publishing Group
Year: 2002
Tongue: English
Weight: 485 KB
Volume: 21
Category: Article
ISSN: 0950-9232
DOI: 10.1038/sj.onc.1206082

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## Abstract ## BACKGROUND Up to 5% of patients with chronic myelogenous leukemia (CML) do not have the Philadelphia (Ph) translocation t(9;22)(q34;q11) or a __bcr__/__abl__ molecular rearrangement. Although the diagnostic criteria of this entity are still under debate, there is general agreement t