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BCR-ABL positive cells and chronic myeloid leukemia in immune suppressed organ transplant recipients

✍ Scribed by Philipp Le Coutre; Petra Reinke; Ruth Neuhaus; Ralf Trappe; Frauke Ringel; Marc Lalancette; Philipp G. Hemmati; Bernd Dörken; Peter T. Daniel


Book ID
114794682
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
109 KB
Volume
84
Category
Article
ISSN
0902-4441

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We have isolated the 3Ј BCR breakpoint junction of a complex BCR-ABL1 rearrangement found in leukemic cells with a cytogenetically normal karyotype, and the corresponding germline fragment that spanned the 3Ј BCR recombination site. Fluorescence in situ hybridization localized the 3Ј BCR recombinati