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BCR-ABL kinase domain mutations in tyrosine kinase inhibitors-naïve and -exposed Southeast Asian chronic myeloid leukemia patients

✍ Scribed by Wanwisa Wongboonma; Wanna Thongnoppakhun; Chirayu U. Auewarakul


Book ID
113956794
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
558 KB
Volume
92
Category
Article
ISSN
0014-4800

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## Abstract We analysed the dynamic change of imatinib‐resistant mutations in BCR‐ABL kinase domain focusing on T315I mutation during dasatinib or nilotinib therapy. Fifty‐five imatinib‐resistant chronic myeloid leukaemia patients (32 patients with imatinib‐resistant mutations and 23 patients witho