✦ LIBER ✦

Characteristics of BCR–ABL kinase domain point mutations in Chinese imatinib-resistant chronic myeloid leukemia patients

✍ Scribed by YaZhen Qin; ShanShan Chen; Bin Jiang; Qian Jiang; Hao Jiang; JinLan Li; LingDi Li; YueYun Lai; YanRong Liu; XiaoJun Huang

Book ID: 105989682
Publisher: Springer
Year: 2010
Tongue: English
Weight: 116 KB
Volume: 90
Category: Article
ISSN: 0939-5555
DOI: 10.1007/s00277-010-1039-5

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## Abstract We analysed the dynamic change of imatinib‐resistant mutations in BCR‐ABL kinase domain focusing on T315I mutation during dasatinib or nilotinib therapy. Fifty‐five imatinib‐resistant chronic myeloid leukaemia patients (32 patients with imatinib‐resistant mutations and 23 patients witho