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Bcr: a negative regulator of the Bcr-Abl oncoprotein in leukemia

✍ Scribed by Arlinghaus, Ralph B


Book ID
110067211
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
174 KB
Volume
21
Category
Article
ISSN
0950-9232

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We have isolated the 3Ј BCR breakpoint junction of a complex BCR-ABL1 rearrangement found in leukemic cells with a cytogenetically normal karyotype, and the corresponding germline fragment that spanned the 3Ј BCR recombination site. Fluorescence in situ hybridization localized the 3Ј BCR recombinati