The proto-oncogene BCL-6 in normal and m
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Huifeng Niu
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Article
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2002
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John Wiley and Sons
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English
β 103 KB
BCL-6 is an important regulator of the immune system. It is required for GC formation and T cell dependent antibody responses. Mice deficient in BCL-6 fail to form GC and mount reduced levels of T cell-dependent antibody responses. BCL-6 (-/-) mice, in addition, develop a massive inflammatory respon