Analysis of PTEN mutations and deletions
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Marion P. Butler; Steven I. Wang; R.S.K. Chaganti; Ramon Parsons; Riccardo Dalla
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Article
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1999
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John Wiley and Sons
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English
β 166 KB
π 2 views
The PTEN gene is involved in 10q23 deletions in several types of cancer, including glioma, melanoma, endometrial and prostate carcinomas. The PTEN gene product is a dual-specificity phosphatase with putative tumor suppressor function. Deletions and rearrangements of 10q22-25 have been reported in Ο³5