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Bcl-2 Gene Expression as a Predictor of Outcome in Diffuse Large B-Cell Lymphoma

โœ Scribed by Shivakumar, Latha; Armitage, James O.


Book ID
119935889
Publisher
CIG Media Group, LP.
Year
2006
Tongue
English
Weight
93 KB
Volume
6
Category
Article
ISSN
1557-9190

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Bcl-6 (LAZ-3) and Bcl-2 gene rearrangements have been respectively reported in 20-35 per cent and 10-25 per cent of diffuse large B-cell lymphomas (DLBCLs). Although these genetic lesions have been associated with different clinical outcomes (i.e., more favourable in Bcl-6 rearranged cases and poore