Bcl-2 Expression in Oral Squamous Cell Carcinoma
✍ Scribed by B. POPOVIĆ; B. JEKIĆ; I. NOVAKOVIĆ; L.J. LUKOVIĆ; Z. TEPAVČEVIĆ; V. JURIŠIĆ; M. VUKADINOVIĆ; J. MILAŠIN
- Book ID
- 111483328
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 114 KB
- Volume
- 1095
- Category
- Article
- ISSN
- 0890-6564
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## Abstract ## Background Apoptosis is a genetically programmed form of cell death, of which caspases are the central components. ## Methods By tissue microarray of 229 cases of oral squamous cell carcinoma (OSCC), we analyzed the immunoexpression of caspases 3, 6, 7, 8, 9, and 10. ## Results
## Background: Inhibition of apoptosis, or programmed cell death, may be critical both in the development of cancer and in determining response to therapy. the authors examined the expression of two related apoptotic inhibitors, bcl-2 and bcl-xl, in pretreatment biopsies from a series of 42 patient