Bcl-2 antisense therapy in B-cell malignant proliferative disorders
β Scribed by Asher Chanan-Khan; Myron S. Czuczman
- Book ID
- 107531855
- Publisher
- Springer
- Year
- 2004
- Tongue
- English
- Weight
- 285 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1527-2729
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## Abstract __Bcl__β2 and survivin are cellular proteins that are known to be inhibitors of apoptosis and are commonly found in malignant tissues, including lymphomas. In previous studies, it has been shown that staining for __bcl__β2 can help distinguish between benign and malignant lymphoid aggre
We compared the expression of the BCL-2 oncoprotein (p26) on B cells from 24 patients with splenic lymphoma with circulating villous lymphocytes (SLVL) with that observed on normal, mature B lymphocytes and on neoplastic B cells from 91 patients with other chronic B-cell malignancies. SLVL B cells s