✦ LIBER ✦

BCL-2 oncoprotein (p26) in splenic lymphoma with villous lymphocytes: A comparative study with other chronic B-cell disorders

✍ Scribed by Lima, Margarida; Teixeira, Maria dos Anjos; Queirós, Maria Luís; Ribeiro dos Santos, Ana Helena; Justiça, Benvindo

Publisher: John Wiley and Sons
Year: 1997
Tongue: English
Weight: 49 KB
Volume: 56
Category: Article
ISSN: 0361-8609
DOI: 10.1002/(sici)1096-8652(199710)56:2<122::aid-ajh9>3.0.co;2-0

No coin nor oath required. For personal study only.

✦ Synopsis

We compared the expression of the BCL-2 oncoprotein (p26) on B cells from 24 patients with splenic lymphoma with circulating villous lymphocytes (SLVL) with that observed on normal, mature B lymphocytes and on neoplastic B cells from 91 patients with other chronic B-cell malignancies. SLVL B cells showed levels of p26 intermediate between those found on normal B lymphocytes and on neoplastic B cells from patients with other chronic B-cell lymphoproliferative disorders. Am.