BBS-1 - A novel inhibitor of the β-secretase pathway of Aβ generation in Alzheimer's disease
✍ Scribed by Beka Solomon
- Book ID
- 118465478
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 41 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1552-5260
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## Abstract Finding inhibitors of the first step of the amyloid cascade, Aβ~42~ generation, is a major goal of Alzheimer's disease drug development. Two target protease activities, β‐and γ‐secretase, were detected more than 10 years ago but progress in this area has been slow because the enzymes we
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