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Bayesian subset analysis in a colorectal cancer clinical trial

โœ Scribed by Dixon, Dennis O.; Simon, Richard


Book ID
127338275
Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
890 KB
Volume
11
Category
Article
ISSN
0277-6715

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Many popular sequential phase II clinical trial designs optimize some criterion subject to constraints on the error probabilities at null and alternative values of the response rate. Such designs may forfeit optimality if one fails to conduct analyses strictly according to plan. Moreover, a decision