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Bayesian methods in clinical trials: a Bayesian analysis of ECOG trials E1684 and E1690

โœ Scribed by Joseph G Ibrahim,Ming-Hui Chen,Haitao Chu


Book ID
126370756
Publisher
BioMed Central
Year
2012
Tongue
English
Weight
367 KB
Volume
12
Category
Article
ISSN
1471-2288

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Many popular sequential phase II clinical trial designs optimize some criterion subject to constraints on the error probabilities at null and alternative values of the response rate. Such designs may forfeit optimality if one fails to conduct analyses strictly according to plan. Moreover, a decision