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Bax is upregulated by p53 signal pathway in the SPE B-induced apoptosis

โœ Scribed by Wei-Ting Lee; Chia-Wen Chang

Book ID
106459251
Publisher
Springer
Year
2010
Tongue
English
Weight
352 KB
Volume
343
Category
Article
ISSN
0300-8177

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## Abstract Paclitaxel exerts its cytotoxic effect by kinetic suppression of microtubules that block cells in the G2/M phase of the cell cycle and trigger apoptosis. To investigate apoptosis induced by paclitaxel in nasopharyngeal carcinoma (NPC), and its possible molecular mechanism of action, the