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Injury-induced apoptosis of neurons in adult brain is mediated by p53-dependent and p53-independent pathways and requires bax

✍ Scribed by Lee J. Martin; Adeel Kaiser; Jonathan W. Yu; Joanne E. Natale; Nael A. Al-Abdulla


Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
688 KB
Volume
433
Category
Article
ISSN
0021-9967

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## Abstract DNA damage is known to be an initiator of neuronal death in neurodegenerative conditions such as Parkinson's and Alzheimer's diseases. The mechanism linking DNA damage and neuronal death is not completely understood. Here, we delineate the mechanism by which neuronal death evoked by DNA