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Basophil histamine release studies in the evaluation of a new anaesthetic agent

✍ Scribed by D. E. Withington

Publisher
SP Birkhäuser Verlag Basel
Year
1988
Tongue
English
Weight
131 KB
Volume
23
Category
Article
ISSN
1420-908X

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✍ Paul D. Siegel; Daniel M. Lewis; Stephen A. Olenchock 📂 Article 📅 1990 🏛 Elsevier Science 🌐 English ⚖ 591 KB

Basophil activation studies commonly rely on the measurement of histamine following extraction and condensation to o-phthalaldehyde (OPT) as a quantitative measurement of degranulation. Specificity has long been recognized as a problem with this method. We have described a new high-performance liqui