Basic mechanisms of IgE-mediated hypersensitivity
โ Scribed by K. Ishizaka
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- English
- Weight
- 661 KB
- Volume
- 1
- Category
- Article
- ISSN
- 0952-7915
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Noncovalent drug presentation leads to the activation of drug-specific T cells. In some patients with hypersensitivity, such a response occurs within hours even upon the first exposure to the drug. Thus, the reaction to the drug might not be due to a classical, primary response, but rather mediated
## Abstract The mechanisms of genetic control of IgE responses are exercised at different immunoโphysiological levels. This study centered upon the development of IgE lineageโspecific regulatory T cells. Herein, we demonstrate the following points: (a) perinatal administration of soluble self IgE m