Basic concepts for genetic testing in common hereditary colorectal cancer syndromes
β Scribed by Lisen Axell; Dennis Ahnen; Kristina Markey
- Publisher
- Current Science Inc.
- Year
- 2005
- Tongue
- English
- Weight
- 449 KB
- Volume
- 1
- Category
- Article
- ISSN
- 1556-3790
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
We thank Ms. Jeanne Wenger and Ms. Linda M. Welch for secretarial assistance.
## Abstract Children who carry a gene mutation for familial adenomatous polyposis are virtually certain to develop colorectal cancer without annual endoscopic screening and a colectomy when polyps appear. Predictive genetic testing can identify children who need regular surveillance. While the medi
## Abstract The estimated lifetime risk for endometrial carcinoma (EC) in hereditary nonpolyposis colorectal cancer syndrome (HNPCC) is 32β60%, thus supporting surveillance. The survival rate of EC patients is, however, favourable questioning the need for surveillance. Yet, the effectiveness of gyn