✦ LIBER ✦

Basic calcium phosphate crystal-induced Egr-1 expression stimulates mitogenesis in human fibroblasts

✍ Scribed by Xiao R. Zeng; Yubo Sun; Leonor Wenger; Herman S. Cheung

Book ID: 116290242
Publisher: Elsevier Science
Year: 2005
Tongue: English
Weight: 696 KB
Volume: 330
Category: Article
ISSN: 0006-291X
DOI: 10.1016/j.bbrc.2005.03.036

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Misoprostol, a prostaglandin E1analogue,

Misoprostol, a prostaglandin E1analogue, inhibits basic calcium phosphate crystal-induced mitogenesis and collagenase accumulation in human fibroblasts

✍ Geraldine M. McCarthy; Peter G. Mitchell; Herman S. Cheung 📂 Article 📅 1993 🏛 Springer 🌐 English ⚖ 520 KB

The role of cyclic-3′,5′-adenosine monop

The role of cyclic-3′,5′-adenosine monophosphate in prostaglandin-mediated inhibition of basic calcium phosphate crystal-induced mitogenesis and collagenase induction in cultured human fibroblasts

✍ McCarthy, Geraldine M.; Cheung, Herman S. 📂 Article 📅 1994 🏛 Elsevier Science 🌐 English ⚖ 794 KB

Basic calcium phosphate crystal–induced

Basic calcium phosphate crystal–induced prostaglandin E2 production in human fibroblasts: Role of cyclooxygenase 1, cyclooxygenase 2, and interleukin-1β

✍ Maria P. Morgan; Linda C. Whelan; John D. Sallis; Conor J. McCarthy; Desmond J. 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 256 KB 👁 2 views

## Abstract ## Objective To elucidate the mechanism of basic calcium phosphate (BCP) crystal–induced prostaglandin E~2~ (PGE~2~) production in human foreskin fibroblasts (HFFs), to identify the signaling pathway involved in the induction of cyclooxygenase 2 (COX‐2) messenger RNA (mRNA) by BCP crys

Microsomal prostaglandin E2 synthase 1 e

Microsomal prostaglandin E2 synthase 1 expression in basic calcium phosphate crystal-stimulated fibroblasts: role of prostaglandin E2 and the EP4 receptor

✍ E.S. Molloy; M.P. Morgan; G.A. Doherty; B. McDonnell; J. O'Byrne; D.J. Fitzgeral 📂 Article 📅 2009 🏛 Elsevier Science 🌐 English ⚖ 309 KB

Basic calcium phosphate crystals up-regu

Basic calcium phosphate crystals up-regulate metalloproteinases but down-regulate tissue inhibitor of metalloproteinase-1 and -2 in human fibroblasts

✍ G. Bai; D.S. Howell; G.A. Howard; B.A. Roos; H.S. Cheung 📂 Article 📅 2001 🏛 Elsevier Science 🌐 English ⚖ 341 KB

HDAC4 contributes to IL-1-induced mPGES-

HDAC4 contributes to IL-1-induced mPGES-1 expression in human synovial fibroblasts through up-regulation of Egr-1 transcriptional activity

✍ Nadir Chabane; Xinfang Li; Hassan Fahmi 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 354 KB 👁 1 views

## Abstract Microsomal prostaglandin E synthase‐1 (mPGES‐1) catalyzes the terminal step in the biosynthesis of PGE~2~, which contributes to many physiopathological processes. We show here that inhibitors of histone deacetylase (HDAC) activity, trichostatin A (TSA), butyric acid (BA), and valproic a