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Misoprostol, a prostaglandin E1analogue, inhibits basic calcium phosphate crystal-induced mitogenesis and collagenase accumulation in human fibroblasts

✍ Scribed by Geraldine M. McCarthy; Peter G. Mitchell; Herman S. Cheung


Book ID
104813829
Publisher
Springer
Year
1993
Tongue
English
Weight
520 KB
Volume
52
Category
Article
ISSN
1432-0827

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Basic calcium phosphate crystal–induced
✍ Maria P. Morgan; Linda C. Whelan; John D. Sallis; Conor J. McCarthy; Desmond J. 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 256 KB 👁 2 views

## Abstract ## Objective To elucidate the mechanism of basic calcium phosphate (BCP) crystal–induced prostaglandin E~2~ (PGE~2~) production in human foreskin fibroblasts (HFFs), to identify the signaling pathway involved in the induction of cyclooxygenase 2 (COX‐2) messenger RNA (mRNA) by BCP crys