Deoxynucleoside phosphoramiditesโA new c
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S.L. Beaucage; M.H. Caruthers
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Article
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1981
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Elsevier Science
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French
โ 302 KB
The development of a new class of nucleoside phosphites is described. These compounds are stable to normal laboratory conditions, are activated by mild acid treatment, and are observed to react essentially quantitatively with protected nucleosides. A recent, key innovation in oligonucleotide synthes