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BASF with new class of enzymes for production of chiral intermediates


Publisher
Elsevier Science
Year
2008
Weight
48 KB
Volume
2008
Category
Article
ISSN
1351-4180

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โœ S.L. Beaucage; M.H. Caruthers ๐Ÿ“‚ Article ๐Ÿ“… 1981 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 302 KB

The development of a new class of nucleoside phosphites is described. These compounds are stable to normal laboratory conditions, are activated by mild acid treatment, and are observed to react essentially quantitatively with protected nucleosides. A recent, key innovation in oligonucleotide synthes