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Base Pairing Configuration and Stability of an Oligonucleotide Duplex Containing a 5-Chlorouracil-Adenine Base Pair

โœ Scribed by Theruvathu, Jacob A.; Kim, Cherine H.; Rogstad, Daniel K.; Neidigh, Jonathan W.; Sowers, Lawrence C.


Book ID
127242500
Publisher
American Chemical Society
Year
2009
Tongue
English
Weight
1002 KB
Volume
48
Category
Article
ISSN
0006-2960

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Oligodeoxyribonucleotides containing 1 -deaza-2'-deoxyadenosine ( = 7-amino-3-(2-deoxy#? -D-erythro -pentofuranosyl)-3H-imidazo[4,5-b]pyridine; lb) form Hoogsteen duplexes. Warson-Crick base pairs cannot be built up due to the absence of N(1). For these studies, oligonucleotide building blocksthe ph