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Base-induced reactions of 3-(α-haloacyl)indoles

✍ Scribed by Jan Bergman; Jan-Erling Bäckvall

Book ID
104247208
Publisher
Elsevier Science
Year
1973
Tongue
French
Weight
176 KB
Volume
14
Category
Article
ISSN
0040-4039

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✦ Synopsis

Forcing conditions, such as powdered sodium hydroxide in reflwing xylene 192 or silver nitrate in ethanol, 3 are necessary to effect Favorskii rearrangements of aryl a-haloalkyl ketones (RCmc0Ar -RCHArCOOH). With 3-(a-haloacyl)indoles , which should be relatively strong acids, 4 as reactants we anticipated the formation of indoleacetic acids under mild conditions along the following reaction path:

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Base-induced reactions of α,β-dihydroxysilanes: stereochemistry and mechanisms
✍ Paul F. Hudrlik; G. Nagendrappa; Ashok K. Kulkarni; Anne M. Hudrlik 📂 Article 📅 1979 🏛 Elsevier Science 🌐 French ⚖ 315 KB

Cyclic d,fi-dihydroxysilanes undergo base-induced elimination reactions if the silicon and the @-OH can be anti; otherwise protiodesilylation predominates.