Base-catalyzed formation of secondary amines from primary amines
β Scribed by Herman G. Richey Jr.; Wayne F. Erickson
- Publisher
- Elsevier Science
- Year
- 1972
- Tongue
- French
- Weight
- 173 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0040-4039
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β¦ Synopsis
Many primary amines when heated with a catalytic amount of a strong base are converted into secondary amines. Sodium hydride (0.2-0.3 mole per mole of amine) CH3(CH2)4CH2NH2 90-110~ 16 hr
π SIMILAR VOLUMES
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Compounds containing both primary and secondary amine moieties in the same molecule were treated sequentially with two equivalents of n-butyllithium at room temperature, two equivalents of TMSCI, one equivalent of nbutyllithium and one equivalent of benzoyl chloride, to afford mono-benzoylated diami