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Base-catalyzed decomposition of N-nitrosobis(2-oxopropyl)amine

✍ Scribed by Boux, Leslie J.; Milligan, Jamie R.; Archer, Michael C.


Book ID
127194148
Publisher
American Chemical Society
Year
1988
Tongue
English
Weight
328 KB
Volume
1
Category
Article
ISSN
0893-228X

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## Abstract N‐Nitrosobis (2‐oxopropyl) amine (BOP), a potent and selective pancreatic carcinogen in the Syrian golden hamster was synthesized with a ^14^C label in the alpha carbon. Oxidation of 2‐hydroxypropyl‐2‐hydroxypropyl‐1‐^14^C‐amine followed by nitrosation with sodium nitrite and hydrochlor